品牌 |
Leading Biology |
貨號 |
APR00064G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Profilin-1 Antibody.
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分子量 |
14957 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Bovine
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靶點(diǎn) |
Profilin-1
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亞型 |
Rabbit IgG
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基因ID |
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UniProt ID |
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功能 |
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR (By similarity).
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總結(jié) |
Profilin is a protein which maintains and shapes cytoskeleton by binding to actin. Profilin 1 has function in breast cancer cell motility, radial migration and glial cell adhesion.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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圖像 |
Western blot analysis of Profilin 1 using lysate From Jurkat cells (Lane 1), 3T3 cells (Lane 2) and rat kidney tissue lysate (Lane 3).
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說明書 |
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數(shù)量 |
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