品牌 |
Leading Biology |
貨號(hào) |
APR06715G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LY6K Antibody.
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分子量 |
18673 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Cytoplasm. Cell membrane; Lipid-anchor, GPI-anchor
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
LY6K; Multiple isoforms of LY6K are known to exist.
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亞型 |
IgG
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通用名 |
CO16
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基因ID |
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UniProt ID |
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功能 |
May play a role in cell growth.
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總結(jié) |
LY6K Antibody: The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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圖像 |
Western blot analysis of LY6K in HeLa cell lysate with LY6K antibody at (A) 1 and (B) 2 μg/mL.
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說(shuō)明書(shū) |
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數(shù)量 |
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