品牌 |
Leading Biology |
貨號(hào) |
APR06764G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEPT1 Antibody.
|
分子量 |
41971 Da
|
細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis Localizes to the midbody during cytokinesis
|
宿主 |
Rabbit
|
種屬反應(yīng)性 |
Human, Mouse, Rat
|
靶點(diǎn) |
SEPT1; At least two isoforms of SEPT1 are known to exist. This antibody is predicted to not cross-react with other Septin protein family members.
|
亞型 |
IgG
|
通用名 |
DIFF6, PNUTL3
|
基因ID |
|
UniProt ID |
|
功能 |
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
|
總結(jié) |
SEPT1 Antibody: SEPT1 (also known as Septin 1), is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. SEPT1 was initially identified through yeast two-hybrid screening as an interaction partner for the serine/threonine kinase Aurora-B. During mitosis, SEPT1 localizes to the spindle pole, suggesting that it may play a role in cytokinesis and chromosome congression.
|
儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, IF, ICC, E
|
圖像 |
Western blot analysis of SEPT1 in Raji cell lysate with SEPT1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry of SEPT1 in Raji cells with SEPT1 antibody at 5 μg/mL.
Immunofluorescence of SEPT1 in Raji cells with SEPT1 antibody at 20 μg/mL.
|
說(shuō)明書 |
|
數(shù)量 |
|