品牌 |
Leading Biology |
貨號(hào) |
APR11546G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Calretinin antibody.
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分子量 |
31540 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
A synthetic peptide corresponding to residues in human Calretinin was used as an immunogen.
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克隆號(hào) |
EP1798
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通用名 |
CAB29
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基因ID |
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UniProt ID |
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功能 |
Calretinin is a calcium-binding protein which is abundant in auditory neurons.
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總結(jié) |
Calretinin (CAB29, calbindin 2) is a calcium binding protein that belongs to calbindin family. It is mainly found in neuronal tissue, high expressed in auditory neurons. It has been implicated in as a calcium buffer, calcium sensor, and as a regulator of apoptosis (1). Calretinin is considered as a specific marker of mesothelllal cells; it is the only marker that has the utility in distinguishing between sarcomatoid mesotheliomas and sarcomatoid renal cell carcinomas (2). It is widely used in the panel of makers for distinguishing mesothlioma from adenocarcinoma. Along with calretinin, the panel includes E-cadherin, CEA, and cytokeratin 5/6 (3).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~1:1000~2000
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別名 |
Calretinin, CR, 29 kDa calbindin, CALB2, CAB29
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圖像 |
Western blot analysis on (A) Fetal Brain (B) Mouse brain and (C) Rat brain lysates using anti-Calretinin RabMAb (Cat. APR11546G).
Immunonohistochemical analysis of paraffin-embedded human brain tissue using anti-Calretinin RabMAb (Cat. APR11546G).
Immunonohistochemical analysis of paraffin-embedded human mesothelioma tissue using anti-Calretinin RabMAb (Cat. APR11546G).
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說明書 |
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數(shù)量 |
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