品牌 |
Leading Biology |
貨號 |
APG02563G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CGB antibody.
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分子量 |
17739 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
|
靶點 |
A synthetic peptide corresponding to residues in human CGB was used as an immunogen.
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克隆號 |
EPR3376
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通用名 |
CGB3
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基因ID |
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UniProt ID |
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功能 |
Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
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總結(jié) |
Human chorionic gonadotropin beta (CGB) belongs to the glycoprotein hormone family that includes the beta subunit of lutenizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) (1). These hormones are central to the endocrine system that regulates normal growth, sexual development, and reproductive function (2). HCG primarily maintains the myometrial and decidual spiral arteries, or the vascular supply of the placenta during the full course of pregnancy (3). It is mainly secreted by the endocrine villous cytotrophoblasts into the maternal compartment and stimulates the formation of the syncytiotrophoblast in an autocrine manner (4). Then HCG binds to the corpus luteum of the ovary, which is stimulated to produce progesterone and maintain the secretory endometrium (5). CGB confers biological specificity, whereas the alpha subunit of HCG is common to all glycoprotein hormones (1).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~1:1000~10000
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別名 |
Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta, CGB, CGB3
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圖像 |
Western blot analysis on (A) JAR and (B) NCCIT cell lysates using anti-CGB RabMAb (Cat. APG02563G).
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說明書 |
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數(shù)量 |
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