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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Cytochrome-C Antibody (oxidase subunit 2)品牌 |
Leading Biology | 貨號 |
APR07491G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytochrome-C antibody (oxidase subunit 2).
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分子量 |
25565 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
A synthetic peptide corresponding to residues in human Cytochrome C Oxidase subunit 2 was used as an immunogen.
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克隆號 |
EPR3314
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通用名 |
COII, COXII, MTCO2
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基因ID |
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UniProt ID |
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功能 |
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
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總結(jié) |
Cytochrome c oxidase subunit 2 (CO2 or MTCO2) is 1 of 3 mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV. Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. It collects electrons from ferrocytochrome c (reduced cytochrome c) and transfers them to oxygen to give water. The energy released is used to transport protons across the mitochondrial inner membrane. Complex IV is composed of 13 polypeptides. Subunits 1, 2 and 3 are encoded by the mtDNA while the remaining subunits are nuclear encoded (1-3).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, IF
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稀釋方法 |
WB~~1:10000~50000
IHC~~1:100~250
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別名 |
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II, MT-CO2, COII, COXII, MTCO2
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圖像 |
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說明書 |
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數(shù)量 |
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