品牌 |
Leading Biology |
貨號 |
APR11508G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BEAN antibody (N-term).
|
分子量 |
28626 Da
|
細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass membrane protein
|
宿主 |
Rabbit
|
種屬反應(yīng)性 |
Human
|
免疫原 |
45-73 aa
|
靶點(diǎn) |
This BEAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human BEAN.
|
亞型 |
Rabbit Ig
|
基因ID |
|
UniProt ID |
|
總結(jié) |
The protein encoded by this gene is one of severalproteins that interact with NEDD4, a member of a family ofubiquitin-protein ligases. These proteins have PY motifs in commonthat bind to the WW domains of NEDD4. NEDD4 is developmentallyregulated, and is highly expressed in embryonic tissues. Mutationsin this gene (i.e., intronic insertions of >100 copies ofpentanucleotide repeats including a (TGGAA)n sequence) areassociated with spinocerebellar ataxia type 31. Alternativelyspliced transcript variants encoding different isoforms have beenfound for this gene.
|
形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
|
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, IHC-P, E
|
稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
|
別名 |
Protein BEAN1, Brain-expressed protein associating with Nedd4 homolog, BEAN, BEAN1
|
圖像 |
BEAN Antibody (N-term) (Cat. APR11508G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BEAN antibody detected the BEAN protein (arrow).
BEAN Antibody (N-term) (Cat. APR11508G)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BEAN Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
|
說明書 |
|
數(shù)量 |
|