全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
AMM07064G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PDE8B antibody (Center).
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分子量 |
98979 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse
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免疫原 |
296-324 aa
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靶點(diǎn) |
This PDE8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in specific signaling in the thyroid gland.
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總結(jié) |
The protein encoded by this gene is a cyclic nucleotidephosphodiesterase (PDE) that catalyzes the hydrolysis of the secondmessenger cAMP. The encoded protein, which does not hydrolyze cGMP,is resistant to several PDE inhibitors. Defects in this gene are acause of autosomal dominant striatal degeneration (ADSD). Severaltranscript variants encoding different isoforms have been found forthis gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
High affinity cAMP-specific and IBMX-insensitive 3', 5'-cyclic phosphodiesterase 8B, HsPDE8B, Cell proliferation-inducing gene 22 protein, PDE8B
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圖像 |
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說(shuō)明書 |
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數(shù)量 |
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