品牌 |
Leading Biology |
貨號 |
APR11990G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GALR1 antibody (Center).
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分子量 |
38953 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
174-200 aa
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靶點 |
This GALR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-200 amino acids from the Central region of human GALR1.
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亞型 |
Rabbit Ig
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通用名 |
GALNR, GALNR1
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基因ID |
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UniProt ID |
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功能 |
Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
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總結(jié) |
GALR1 elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
WB~~1:1000
FC~~1:10~50
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別名 |
Galanin receptor type 1, GAL1-R, GALR-1, GALR1, GALNR, GALNR1
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圖像 |
All lanes : Anti-GALR1 Antibody (Center) at 1:1000 dilution
Lane 1: CCRF-CEM whole cell lysate
Lane 2: K562 whole cell lysate
Lysates/proteins at 20 μg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 39 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
GALR1 Antibody (Center) (Cat. APR11990G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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說明書 |
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數(shù)量 |
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