品牌 |
Leading Biology |
貨號 |
APR16067G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Ga15/16 antibody.
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分子量 |
43568 Da
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
Ga 15/16
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亞型 |
Rabbit IgG
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通用名 |
GNA16
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基因ID |
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UniProt ID |
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功能 |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
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總結 |
Gα16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Gα16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-β and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Gα15, a mouse orthologue of human Gα16, causes reduced C5α receptor signaling. Gα16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB
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別名 |
G alpha binding protein
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圖像 |
Western blot analysis of Gα-15 expression in 3T3 cell lysate.
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說明書 |
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數(shù)量 |
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