品牌 |
Leading Biology |
貨號 |
APR16165G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Glycerol kinase (GPK2) antibody (C-term).
|
分子量 |
H=61;M=61 KDa
|
細(xì)胞定位 |
Antigen Cellular Localization:
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=In sperm the majority of the enzyme is bound to mitochondria.
|
宿主 |
Rabbit
|
種屬反應(yīng)性 |
Human
|
免疫原 |
487-515 aa
|
靶點(diǎn) |
This Glycerol kinase (GPK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-515 amino acids from the C-terminal region of human Glycerol kinase (GPK2).
|
通用名 |
GKP2, GKTA
|
基因ID |
|
UniProt ID |
|
功能 |
Key enzyme in the regulation of glycerol uptake and metabolism.
|
總結(jié) |
The human glycerol kinase gene family consists of at least 3 expressed loci. The GK1 locus on Xp21.3 is the site of mutations (deletions) causing glycerol kinase deficiency. It comprises 19 exons and is probably ancestral to several other genes which, because they are intronless, are suspected of having arisen by reverse transcriptase mediated events. These include 2 genes on chromosome 4. They are expressed as a single mRNA species in testis where expression is at a high level.
|
形式 |
Liquid. In PBS containing 0.02% sodium azide.
|
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, IHC-P
|
稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
|
別名 |
Glycerol kinase 2, GK 2, Glycerokinase 2, ATP:glycerol 3-phosphotransferase 2, Glycerol kinase, testis specific 2, GK2, GKP2, GKTA
|
圖像 |
All lanes : Anti-GPK2/3 Antibody (T502) at 1:1000 dilution
Lane 1: human liver lysate
Lane 2: Jurkat whole cell lysate
Lysates/proteins at 20 μg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 61 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
|
說明書 |
|
數(shù)量 |
|