品牌 |
Leading Biology |
貨號 |
APR03954G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL9R Antibody (Center).
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分子量 |
57147 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Secreted
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
170-199 aa
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靶點(diǎn) |
This IL9R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-199 amino acids from the Central region of human IL9R.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
This is a receptor for interleukin-9.
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總結(jié) |
The protein encoded by this gene is a cytokine receptorthat specifically mediates the biological effects of interleukin 9(IL9). The functional IL9 receptor complex requires this protein aswell as the interleukin 2 receptor, gamma (IL2RG), a common gammasubunit shared by the receptors of many different cytokines. Theligand binding of this receptor leads to the activation of variousJAK kinases and STAT proteins, which connect to different biologicresponses. This gene is located at the pseudoautosomal regions of Xand Y chromosomes. Genetic studies suggested an association of thisgene with the development of asthma. Multiple pseudogenes onchromosome 9, 10, 16, and 18 have been described. Alternativelyspliced transcript variants have been found for this gene.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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圖像 |
Anti-IL9R Antibody (Center) at 1:1000 dilution + Jurkat whole cell lysate
Lysates/proteins at 20 μg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 57 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
IL9R Antibody (Center) (APR03954G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IL9R Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
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說明書 |
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數(shù)量 |
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