品牌 |
Leading Biology |
貨號(hào) |
APG02662G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CLN8 antibody (C-term).
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分子量 |
32787 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
251-280 aa
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靶點(diǎn) |
This CLN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-280 amino acids from the C-terminal region of human CLN8.
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亞型 |
Rabbit Ig
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通用名 |
C8orf61
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基因ID |
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UniProt ID |
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功能 |
Could play a role in cell proliferation during neuronal differentiation and in protection against cell death.
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總結(jié) |
This gene encodes a transmembrane protein belonging to afamily of proteins containing TLC domains, which are postulated tofunction in lipid synthesis, transport, or sensing. The proteinlocalizes to the endoplasmic reticulum (ER), and may recyclebetween the ER and ER-Golgi intermediate compartment. Mutations inthis gene are associated with progressive epilepsy with mentalretardation (EMPR), which is a subtype of neuronal ceroidlipofuscinoses (NCL). Patients with mutations in this gene havealtered levels of sphingolipid and phospholipids in the brain.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Protein CLN8, CLN8, C8orf61
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圖像 |
CLN8 Antibody (C-term)(Cat. APG02662G) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CLN8 antibody detected the CLN8 protein (arrow).
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說明書 |
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數(shù)量 |
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