品牌 |
Leading Biology |
貨號(hào) |
AMM07251G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PLIN3 antibody (Center).
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分子量 |
47075 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet. Note=Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
230-257 aa
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靶點(diǎn) |
This PLIN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-257 amino acids from the Central region of human PLIN3.
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亞型 |
Rabbit Ig
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通用名 |
M6PRBP1, TIP47
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基因ID |
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UniProt ID |
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功能 |
Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
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總結(jié) |
Mannose 6-phophate receptors (MPRs) deliver lysosomalhydrolase from the Golgi to endosomes and then return to the Golgicomplex. The protein encoded by this gene interacts with thecytoplasmic domains of both cation-independent and cation-dependentMPRs, and is required for endosome-to-Golgi transport. This proteinalso binds directly to the GTPase RAB9 (RAB9A), a member of the RASoncogene family. The interaction with RAB9 has been shown toincrease the affinity of this protein for its cargo. Multipletranscript variants encoding different isoforms have been found forthis gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Perilipin-3, 47 kDa mannose 6-phosphate receptor-binding protein, 47 kDa MPR-binding protein, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Placental protein 17, PP17, PLIN3, M6PRBP1, TIP47
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圖像 |
All lanes : Anti-PLIN3 Antibody (Center) at 1:1000 dilution
Lane 1: Daudi whole cell lysate
Lane 2: K562 whole cell lysate
Lysates/proteins at 20 μg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 47 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
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說明書 |
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數(shù)量 |
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