品牌 |
Leading Biology |
貨號 |
APR16350G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-Neurobeachin antibody.
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分子量 |
327822 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein
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宿主 |
Goat
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種屬反應性 |
Human, Mouse
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亞型 |
IgG
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通用名 |
BCL8B, KIAA1544, LYST2
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基因ID |
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UniProt ID |
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功能 |
Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity).
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總結(jié) |
This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. Alternatively spliced transcript variants may exist, but their full-length nature has not been determined.
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC, E
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別名 |
Neurobeachin, Lysosomal-trafficking regulator 2, Protein BCL8B, NBEA, BCL8B, KIAA1544, LYST2
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圖像 |
APR16350G (5 μg/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
APR16350G (1 μg/ml) staining of 1) untransfected HEK293T cells 2) HEK293T cells transfected with mouse NBEA. Detected by chemiluminescence. Data kindly provided by Professor John Creemers, K.U. Leuven, Belgium
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說明書 |
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數(shù)量 |
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